Pediatric Ocular Surface Squamous Neoplasia in the Absence of Known Risk Factors and Systemic Conditions

Ocular surface squamous neoplasia (OSSN) includes precancerous and cancerous epithelial lesions of the conjunctiva and cornea, typically affecting older adults with risk factors like immunosuppression, sun exposure, and viral infections. Pediatric OSSN is rare, with few reported cases. We present a series of 16 pediatric and adolescent OSSN cases without known genetic or infectious risk factors.